KRASG12D, pulmonary LCH, and atorvastatin

Atorvastatin in pulmonary arterial hypertension (APATH) study.

Statins have been shown to both prevent and attenuate pulmonary hypertension in animal models. This study investigates the potential therapeutic benefits of atorvastatin as an affordable treatment for pulmonary hypertension patients. 220 patients with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH) were randomised, double-blind, to receive atrovast...

LCH : The Symptoms , Diagnosis and Treatment LCH : The Symptoms , Diagnosis and Treatment

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This article offers a history of the English legal category monster, a legal category that entered English law in the mid-thirteenth and survived until the mid-nineteenth century. The aim of the article is to provide a close textual analysis of an otherwise absent legal history and to locate law’s monsters, and the anxieties that they suggest, within their appropriate contexts: social, politica...

Light Composite Higgs: Lch @ Lhc

Here I summarize some of the salient features of technicolor theories with technifermions in higher dimensional representations of the technicolor gauge group. The expected phase diagram as function of number of flavors and colors for the two index (anti)symmetric representation of the gauge group is reviewed. After having constructed the simplest walking technicolor theory one can show that it...

Salvage treatment of relapsed/refractory LCH

The Langerhan’s cell histiocytosis (LCH) is a rare hematologic disorder of all age group, and the classification of LCH as a neoplasm of myeloid origin was introduced with the current observation of recurrent BRAF mutation in LCH patients. LCH shows broad spectrum of clinical manifestations from single system involvement to wide spread multi-system (MS) disease, and this clinical variety is ass...